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Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches

The interaction between macromolecular proteins and small molecule ligands is an essential component of cellular function. Such ligands may include enzyme substrates, molecules involved in cellular signalling or pharmaceutical drugs. Together with biophysical techniques used to assess the thermodyna...

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Detalles Bibliográficos
Autores principales:	Hough, Michael A., Prischi, Filippo, Worrall, Jonathan A. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899996/ https://www.ncbi.nlm.nih.gov/pubmed/36756363 http://dx.doi.org/10.3389/fmolb.2023.1113762

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