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Pharmacogenomics and health disparities, are we helping?

Pharmacogenomics has been at the forefront of precision medicine during the last few decades. Precision medicine carries the potential of improving health outcomes at both the individual as well as population levels. To harness the benefits of its initiatives, careful dissection of existing health d...

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Detalles Bibliográficos
Autores principales: Shaaban, Sherin, Ji, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900000/
https://www.ncbi.nlm.nih.gov/pubmed/36755573
http://dx.doi.org/10.3389/fgene.2023.1099541
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author Shaaban, Sherin
Ji, Yuan
author_facet Shaaban, Sherin
Ji, Yuan
author_sort Shaaban, Sherin
collection PubMed
description Pharmacogenomics has been at the forefront of precision medicine during the last few decades. Precision medicine carries the potential of improving health outcomes at both the individual as well as population levels. To harness the benefits of its initiatives, careful dissection of existing health disparities as they relate to precision medicine is of paramount importance. Attempting to address the existing disparities at the early stages of design and implementation of these efforts is the only guarantee of a successful just outcome. In this review, we glance at a few determinants of existing health disparities as they intersect with pharmacogenomics research and implementation. In our opinion, highlighting these disparities is imperative for the purpose of researching meaningful solutions. Failing to identify, and hence address, these disparities in the context of the current and future precision medicine initiatives would leave an already strained health system, even more inundated with inequality.
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spelling pubmed-99000002023-02-07 Pharmacogenomics and health disparities, are we helping? Shaaban, Sherin Ji, Yuan Front Genet Genetics Pharmacogenomics has been at the forefront of precision medicine during the last few decades. Precision medicine carries the potential of improving health outcomes at both the individual as well as population levels. To harness the benefits of its initiatives, careful dissection of existing health disparities as they relate to precision medicine is of paramount importance. Attempting to address the existing disparities at the early stages of design and implementation of these efforts is the only guarantee of a successful just outcome. In this review, we glance at a few determinants of existing health disparities as they intersect with pharmacogenomics research and implementation. In our opinion, highlighting these disparities is imperative for the purpose of researching meaningful solutions. Failing to identify, and hence address, these disparities in the context of the current and future precision medicine initiatives would leave an already strained health system, even more inundated with inequality. Frontiers Media S.A. 2023-01-23 /pmc/articles/PMC9900000/ /pubmed/36755573 http://dx.doi.org/10.3389/fgene.2023.1099541 Text en Copyright © 2023 Shaaban and Ji. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Shaaban, Sherin
Ji, Yuan
Pharmacogenomics and health disparities, are we helping?
title Pharmacogenomics and health disparities, are we helping?
title_full Pharmacogenomics and health disparities, are we helping?
title_fullStr Pharmacogenomics and health disparities, are we helping?
title_full_unstemmed Pharmacogenomics and health disparities, are we helping?
title_short Pharmacogenomics and health disparities, are we helping?
title_sort pharmacogenomics and health disparities, are we helping?
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900000/
https://www.ncbi.nlm.nih.gov/pubmed/36755573
http://dx.doi.org/10.3389/fgene.2023.1099541
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