FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer’s lactate

OBJECTIVES: Normal saline (NS) and Ringer’s lactate (RL) are the most common crystalloids used for fluid therapy. Despite evidence of possible harm associated with NS (eg, hyperchloremic metabolic acidosis, impaired kidney function and death), few large multi-centre randomised trials have evaluated...

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Detalles Bibliográficos
Autores principales: McIntyre, Lauralyn Ann, Fergusson, Dean A, McArdle, Tracy, Fox-Robichaud, Alison, English, Shane W, Martin, Claudio, Marshall, John, Cook, Deborah J, Graham, Ian D, Hawken, Steven, McCartney, Colin, Menon, Kusum, Saginur, Raphael, Seely, Andrew, Stiell, Ian, Thavorn, Kednapa, Weijer, Charles, Iyengar, Akshai, Muscedere, John, Forster, Alan J, Taljaard, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Medical Management
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900065/
https://www.ncbi.nlm.nih.gov/pubmed/36737087
http://dx.doi.org/10.1136/bmjopen-2022-067142

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