Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats

OBJECTIVES: Spondyloarthritis (SpA) is known as series of immune-mediated inflammatory disease of the axial and peripheral joints. Human leucocyte antigen (HLA)-B27 is a genetic risk factor for SpA. Recent evidence suggests that the interleukin −17 (IL17) axis strongly contributes to SpA. This study...

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Detalles Bibliográficos
Autores principales: Hayashi, Hiroki, Sun, Jiao, Yanagida, Yuka, Yoshida, Shota, Baba, Satoshi, Tenma, Akiko, Toyoura, Masayoshi, Kawabata, Sotaro, Ehara, Takako, Asaki, Ryoko, Sakaguchi, Makoto, Tomioka, Hideki, Shimamura, Munehisa, Morishita, Ryuichi, Rakugi, Hiromi, Tomita, Tetsuya, Nakagami, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Spondyloarthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900070/
https://www.ncbi.nlm.nih.gov/pubmed/36737108
http://dx.doi.org/10.1136/rmdopen-2022-002851

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