Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review

In recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Chi, Du, Yuwei, Li, Yuegang, Xu, Huimian, Zhu, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900096/
https://www.ncbi.nlm.nih.gov/pubmed/36755859
http://dx.doi.org/10.3389/fonc.2022.1003959
_version_ 1784882771437551616
author Xue, Chi
Du, Yuwei
Li, Yuegang
Xu, Huimian
Zhu, Zhi
author_facet Xue, Chi
Du, Yuwei
Li, Yuegang
Xu, Huimian
Zhu, Zhi
author_sort Xue, Chi
collection PubMed
description In recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predictors of therapeutic response to immune checkpoint inhibitors, such as microsatellite instability (MSI), and therapeutic targets of molecular targeted therapy, such as human epidermal growth factor receptor 2 (HER-2). Therefore, tumor budding is a major element in the formulation of risk stratification and precision medicine strategies for patients with gastric cancer.
format Online
Article
Text
id pubmed-9900096
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-99000962023-02-07 Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review Xue, Chi Du, Yuwei Li, Yuegang Xu, Huimian Zhu, Zhi Front Oncol Oncology In recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predictors of therapeutic response to immune checkpoint inhibitors, such as microsatellite instability (MSI), and therapeutic targets of molecular targeted therapy, such as human epidermal growth factor receptor 2 (HER-2). Therefore, tumor budding is a major element in the formulation of risk stratification and precision medicine strategies for patients with gastric cancer. Frontiers Media S.A. 2023-01-23 /pmc/articles/PMC9900096/ /pubmed/36755859 http://dx.doi.org/10.3389/fonc.2022.1003959 Text en Copyright © 2023 Xue, Du, Li, Xu and Zhu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Xue, Chi
Du, Yuwei
Li, Yuegang
Xu, Huimian
Zhu, Zhi
Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title_full Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title_fullStr Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title_full_unstemmed Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title_short Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
title_sort tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: a mini review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900096/
https://www.ncbi.nlm.nih.gov/pubmed/36755859
http://dx.doi.org/10.3389/fonc.2022.1003959
work_keys_str_mv AT xuechi tumorbuddingasapredictorforprognosisandtherapeuticresponseingastriccanceraminireview
AT duyuwei tumorbuddingasapredictorforprognosisandtherapeuticresponseingastriccanceraminireview
AT liyuegang tumorbuddingasapredictorforprognosisandtherapeuticresponseingastriccanceraminireview
AT xuhuimian tumorbuddingasapredictorforprognosisandtherapeuticresponseingastriccanceraminireview
AT zhuzhi tumorbuddingasapredictorforprognosisandtherapeuticresponseingastriccanceraminireview

Ejemplares similares