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MFR-DTA: a multi-functional and robust model for predicting drug–target binding affinity and region

MOTIVATION: Recently, deep learning has become the mainstream methodology for drug–target binding affinity prediction. However, two deficiencies of the existing methods restrict their practical applications. On the one hand, most existing methods ignore the individual information of sequence element...

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Detalles Bibliográficos
Autores principales: Hua, Yang, Song, Xiaoning, Feng, Zhenhua, Wu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900210/
https://www.ncbi.nlm.nih.gov/pubmed/36708000
http://dx.doi.org/10.1093/bioinformatics/btad056