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CAPLA: improved prediction of protein–ligand binding affinity by a deep learning approach based on a cross-attention mechanism

MOTIVATION: Accurate and rapid prediction of protein–ligand binding affinity is a great challenge currently encountered in drug discovery. Recent advances have manifested a promising alternative in applying deep learning-based computational approaches for accurately quantifying binding affinity. The...

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Detalles Bibliográficos
Autores principales:	Jin, Zhi, Wu, Tingfang, Chen, Taoning, Pan, Deng, Wang, Xuejiao, Xie, Jingxin, Quan, Lijun, Lyu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900214/ https://www.ncbi.nlm.nih.gov/pubmed/36688724 http://dx.doi.org/10.1093/bioinformatics/btad049

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