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PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data

More than half of human genes exercise alternative polyadenylation (APA) and generate mRNA transcripts with varying 3’ untranslated regions (UTR). However, current computational approaches for identifying cleavage and polyadenylation sites (C/PASs) and quantifying 3’UTR length changes from bulk RNA-...

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Detalles Bibliográficos
Autores principales:	Jonnakuti, Venkata Soumith, Wagner, Eric J., Maletić-Savatić, Mirjana, Liu, Zhandong, Yalamanchili, Hari Krishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900750/ https://www.ncbi.nlm.nih.gov/pubmed/36747700 http://dx.doi.org/10.1101/2023.01.23.523471

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