Cargando…
CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION
For cell instance segmentation on Electron Microscopy (EM) images, state-of-the-art methods either conduct pixel-wise classification or follow a detection and segmentation manner. However, both approaches suffer from the enormous cell instances of EM images where cells are tightly close to each othe...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900774/ https://www.ncbi.nlm.nih.gov/pubmed/36747649 http://dx.doi.org/10.1101/2023.01.24.525387 |
_version_ | 1784882915984801792 |
---|---|
author | Duan, Bin Cao, Jianfeng Wang, Wei Cai, Dawen Yan, Yan |
author_facet | Duan, Bin Cao, Jianfeng Wang, Wei Cai, Dawen Yan, Yan |
author_sort | Duan, Bin |
collection | PubMed |
description | For cell instance segmentation on Electron Microscopy (EM) images, state-of-the-art methods either conduct pixel-wise classification or follow a detection and segmentation manner. However, both approaches suffer from the enormous cell instances of EM images where cells are tightly close to each other and show inconsistent morphological properties and/or homogeneous appearances. This fact can easily lead to over-segmentation and under-segmentation problems for model prediction, i.e., falsely splitting and merging adjacent instances. In this paper, we propose a novel approach incorporating non-local correlation in the embedding space to make pixel features distinct or similar to their neighbors and thus address the over- and under-segmentation problems. We perform experiments on five different EM datasets where our proposed method yields better results than several strong baselines. More importantly, by using non-local correlation, we observe fewer false separations within one cell and fewer false fusions between cells. |
format | Online Article Text |
id | pubmed-9900774 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-99007742023-02-07 CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION Duan, Bin Cao, Jianfeng Wang, Wei Cai, Dawen Yan, Yan bioRxiv Article For cell instance segmentation on Electron Microscopy (EM) images, state-of-the-art methods either conduct pixel-wise classification or follow a detection and segmentation manner. However, both approaches suffer from the enormous cell instances of EM images where cells are tightly close to each other and show inconsistent morphological properties and/or homogeneous appearances. This fact can easily lead to over-segmentation and under-segmentation problems for model prediction, i.e., falsely splitting and merging adjacent instances. In this paper, we propose a novel approach incorporating non-local correlation in the embedding space to make pixel features distinct or similar to their neighbors and thus address the over- and under-segmentation problems. We perform experiments on five different EM datasets where our proposed method yields better results than several strong baselines. More importantly, by using non-local correlation, we observe fewer false separations within one cell and fewer false fusions between cells. Cold Spring Harbor Laboratory 2023-01-25 /pmc/articles/PMC9900774/ /pubmed/36747649 http://dx.doi.org/10.1101/2023.01.24.525387 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator. |
spellingShingle | Article Duan, Bin Cao, Jianfeng Wang, Wei Cai, Dawen Yan, Yan CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title | CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title_full | CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title_fullStr | CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title_full_unstemmed | CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title_short | CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION |
title_sort | cell instance segmentation via multi-scale non-local correlation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900774/ https://www.ncbi.nlm.nih.gov/pubmed/36747649 http://dx.doi.org/10.1101/2023.01.24.525387 |
work_keys_str_mv | AT duanbin cellinstancesegmentationviamultiscalenonlocalcorrelation AT caojianfeng cellinstancesegmentationviamultiscalenonlocalcorrelation AT wangwei cellinstancesegmentationviamultiscalenonlocalcorrelation AT caidawen cellinstancesegmentationviamultiscalenonlocalcorrelation AT yanyan cellinstancesegmentationviamultiscalenonlocalcorrelation |