Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response

CNS inflammation triggers activation of the integrated stress response (ISR). We previously reported that prolonging the ISR protects remyelinating oligodendrocytes and promotes remyelination in the presence of inflammation (Chen et al., eLife, 2021). However, the exact mechanisms through which this...

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Detalles Bibliográficos
Autores principales: Chen, Yanan, Quan, Songhua, Patil, Vaibhav, Kunjamma, Rejani B., Tokars, Haley M., Leisten, Eric D., Chan, Jonah, Wong, Yvette, Popko, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900777/
https://www.ncbi.nlm.nih.gov/pubmed/36747743
http://dx.doi.org/10.1101/2023.01.23.525156

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