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Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages

N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) is a zinc metallohydrolase that hydrolyzes N-acyl-phosphatidylethanolamine (NAPEs) to form N-acyl-ethanolamides (NAEs) and phosphatidic acid. Several lines of evidence suggest that reduced NAPE-PLD activity could contribute to ca...

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Detalles Bibliográficos
Autores principales: Zarrow, Jonah E., Alli-Oluwafuyi, Abdul-Musawwir, Youwakim, Cristina M., Kim, Kwangho, Jenkins, Andrew N., Suero, Isabelle C., Jones, Margaret R., Mashhadi, Zahra, Mackie, Kenneth P., Waterson, Alex G., Doran, Amanda C., Sulikowski, Gary A., Davies, Sean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900783/
https://www.ncbi.nlm.nih.gov/pubmed/36747693
http://dx.doi.org/10.1101/2023.01.25.525554

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