Characterization of the zebrafish gabra1(sa43718/sa43718) germline loss of function allele confirms a function for Gabra1 in motility and nervous system development

Mutation of the GABRA1 gene is associated with neurodevelopmental defects and epilepsy. GABRA1 encodes for the α1 subunit of the gamma-aminobutyric acid type A receptor (GABA(A)R), which regulates the fast inhibitory impulses of the nervous system. Multiple model systems have previously been develop...

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Detalles Bibliográficos
Autores principales: Paz, David, Reyes-Nava, Nayeli G., Pinales, Briana E., Perez, Isaiah, Gil, Claudia B., Gonzales, Annalise V., Grajeda, Brian, Estevao, Igor L., Ellis, Cameron C., Castro, Victoria L., Quintana, Anita M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900897/
https://www.ncbi.nlm.nih.gov/pubmed/36747751
http://dx.doi.org/10.1101/2023.01.27.525860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900897/
https://www.ncbi.nlm.nih.gov/pubmed/36747751
http://dx.doi.org/10.1101/2023.01.27.525860

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