Cargando…

Role and mechanism of CD90(+) fibroblasts in inflammatory diseases and malignant tumors

Fibroblasts are highly heterogeneous mesenchymal stromal cells, and different fibroblast subpopulations play different roles. A subpopulation of fibroblasts expressing CD90, a 25–37 kDa glycosylphosphatidylinositol anchored protein, plays a dominant role in the fibrotic and pro-inflammatory state. I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Feng, Gao, Mengxiang, Liao, Shan, Zhou, Zihua, Luo, Gengqiu, Zhou, Yanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900913/ https://www.ncbi.nlm.nih.gov/pubmed/36747131 http://dx.doi.org/10.1186/s10020-023-00616-7

Ejemplares similares

Effects of altered glycolysis levels on CD8(+) T cell activation and function
por: Cao, Jiaying, et al.
Publicado: (2023)

Integrative Analysis Identified CD38 As a Key Node That Correlates Highly with Immunophenotype, Chemoradiotherapy Resistance, And Prognosis of Head and Neck Cancer
por: He, Zhengxi, et al.
Publicado: (2023)

Lactotransferrin expression is downregulated and affects the mitogen-activated protein kinase pathway in gastric cancer
por: Luo, Gengqiu, et al.
Publicado: (2021)

Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions
por: Zhou, Jing, et al.
Publicado: (2022)

Defining Skin Fibroblastic Cell Types Beyond CD90
por: Jiang, Dongsheng, et al.
Publicado: (2018)

CD105(+)CD90(+)CD13(+) identifies a clonogenic subset of adventitial lung fibroblasts
por: Kadefors, Måns, et al.
Publicado: (2021)

Differential Inductive Signaling of CD90(+) Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells
por: Pascal, Laura E., et al.
Publicado: (2011)

Effects of glycolysis on the polarization and function of tumor-associated macrophages (Review)
por: Cao, Jiaying, et al.
Publicado: (2023)

YWHAH activates the HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect the proliferation of gastric cancer cells
por: HE, JUNYU, et al.
Publicado: (2023)

Molecular Mechanism of Tumor Cell Immune Escape Mediated by CD24/Siglec-10
por: Yin, Shan-Shan, et al.
Publicado: (2020)

Analysis of the prognostic, diagnostic and immunological role of HSP90α in malignant tumors
por: Yuan, Zhimin, et al.
Publicado: (2022)

CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes
por: Dudli, Stefan, et al.
Publicado: (2022)

CD90/THY1 is over-expressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker
por: True, Lawrence D, et al.
Publicado: (2010)

Overexpression of CD90 (Thy-1) in Pancreatic Adenocarcinoma Present in the Tumor Microenvironment
por: Zhu, Jianhui, et al.
Publicado: (2014)

Distinct Roles of Molecular Chaperones HSP90α and HSP90β in the Biogenesis of KCNQ4 Channels
por: Gao, Yanhong, et al.
Publicado: (2013)

Inhibitory effects of (90)Sr/(90)Y β-irradiation on alkali burn-induced corneal neovascularization in rats
por: LIN, YUANQIANG, et al.
Publicado: (2016)

Synthesis of cytoskeletal and contractile proteins by cultured IMR-90 fibroblasts
Publicado: (1985)

Degradation of proteins microinjected into IMR-90 human diploid fibroblasts
Publicado: (1981)

CXCR1 promotes malignant behavior of gastric cancer cells in vitro and in vivo in AKT and ERK1/2 phosphorylation
por: Wang, Junpu, et al.
Publicado: (2023)

Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression
por: McCarthy, James B., et al.
Publicado: (2018)

A pan-cancer analysis of copper homeostasis-related gene lipoyltransferase 1: Its potential biological functions and prognosis values
por: Liu, Ying, et al.
Publicado: (2022)

Targeting of CD163(+) Macrophages in Inflammatory and Malignant Diseases
por: Skytthe, Maria K., et al.
Publicado: (2020)

The role of CD180 in hematological malignancies and inflammatory disorders
por: Edwards, Kurtis, et al.
Publicado: (2023)

Decreased CD90 expression in human mesenchymal stem cells by applying mechanical stimulation
por: Wiesmann, Anne, et al.
Publicado: (2006)

Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil
por: WANG, JUNPU, et al.
Publicado: (2016)

Effects and mechanisms of Eps8 on the biological behaviour of malignant tumours
por: Luo, Kaili, et al.
Publicado: (2021)

Clinicopathological features of superficial CD34-positive fibroblastic tumor
por: Ding, Li, et al.
Publicado: (2021)

The Chaperone System in Salivary Glands: Hsp90 Prospects for Differential Diagnosis and Treatment of Malignant Tumors
por: Basset, Charbel A., et al.
Publicado: (2022)

Prognostic roles for fibroblast growth factor receptor family members in malignant peripheral nerve sheath tumor
por: Zhou, Wenya, et al.
Publicado: (2016)

CD49b, CD87, and CD95 Are Markers for Activated Cancer-Associated Fibroblasts Whereas CD39 Marks Quiescent Normal Fibroblasts in Murine Tumor Models
por: Agorku, David J., et al.
Publicado: (2019)

Corrigendum: Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression
por: McCarthy, James B., et al.
Publicado: (2018)

Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury
por: Chen, Zelin, et al.
Publicado: (2017)

Mechanisms of Hsp90 regulation
por: Prodromou, Chrisostomos
Publicado: (2016)

Regulatory Mechanisms of Hsp90
por: Prodromou, Chrisostomos
Publicado: (2017)

CD38 in cancer-associated fibroblasts promotes pro-tumoral activity
por: Ben Baruch, Bar, et al.
Publicado: (2020)

Superficial CD34-Positive Fibroblastic Tumor: Two Case Reports
por: Yim, Jung Eun, et al.
Publicado: (2023)

Progress of Artificial Intelligence in Gynecological Malignant Tumors
por: Zhou, Jie, et al.
Publicado: (2020)

Emerging Role and Mechanism of circRNAs in Pediatric Malignant Solid Tumors
por: Shen, Qiyang, et al.
Publicado: (2022)

CD90 and CD24 Co-Expression Is Associated with Pancreatic Intraepithelial Neoplasias
por: Pei, Xiucong, et al.
Publicado: (2016)

Long-term cardiovascular mortality risk in patients with bladder cancer: a real-world retrospective study of 129,765 cases based on the SEER database
por: Liao, Jia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_arij2o18bri29t52mg4h6a0pcj