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Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments

High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can be a challenge. Here, we introduce Samui, a performant and interactive ima...

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Detalles Bibliográficos
Autores principales: Sriworarat, Chaichontat, Nguyen, Annie, Eagles, Nicholas J., Collado-Torres, Leonardo, Martinowich, Keri, Maynard, Kristen R., Hicks, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900917/
https://www.ncbi.nlm.nih.gov/pubmed/36747726
http://dx.doi.org/10.1101/2023.01.28.525943
Descripción
Sumario:High-resolution and multiplexed imaging techniques are giving us an increasingly detailed observation of a biological system. However, sharing, exploring, and customizing the visualization of large multidimensional images can be a challenge. Here, we introduce Samui, a performant and interactive image visualization tool that runs completely in the web browser. Samui is specifically designed for fast image visualization and annotation and enables users to browse through large images and their selected features within seconds of receiving a link. We demonstrate the broad utility of Samui with images generated with two platforms: Vizgen MERFISH and 10x Genomics Visium Spatial Gene Expression. Samui along with example datasets is available at https://samuibrowser.com.