Using mechanistic models and machine learning to design single-color multiplexed Nascent Chain Tracking experiments

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mRNA translation is the ubiquitous cellular process of reading messenger-RNA strands into functional proteins. Over the past decade, large strides in microscopy techniques have allowed observation of mRNA translation at a single-molecule resolution for self-consistent time-series measurements in liv...

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Detalles Bibliográficos
Autores principales: Raymond, William S., Ghaffari, Sadaf, Aguilera, Luis U., Ron, Eric, Morisaki, Tatsuya, Fox, Zachary R., May, Michael P., Stasevich, Timothy J., Munsky, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900927/
https://www.ncbi.nlm.nih.gov/pubmed/36747627
http://dx.doi.org/10.1101/2023.01.25.525583
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