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scMINER: a mutual information-based framework for identifying hidden drivers from single-cell omics data
The sparse nature of single-cell omics data makes it challenging to dissect the wiring and rewiring of the transcriptional and signaling drivers that regulate cellular states. Many of the drivers, referred to as “hidden drivers”, are difficult to identify via conventional expression analysis due to...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901036/ https://www.ncbi.nlm.nih.gov/pubmed/36747874 http://dx.doi.org/10.21203/rs.3.rs-2476875/v1 |