Cargando…

Blockage of glycolysis by targeting PFKFB3 suppresses the development of infantile hemangioma

BACKGROUND: Infantile hemangioma (IH) is the most common tumor among infants, but the exact pathogenesis of IH is largely unknown. Our previous study revealed that glucose metabolism may play an important role in the pathogenesis of IH and that the inhibition of the glycolytic key enzyme phosphofruc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Kaiying, Qiu, Tong, Zhou, Jiangyuan, Gong, Xue, Zhang, Xuepeng, Lan, Yuru, Zhang, Zixin, Ji, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901151/ https://www.ncbi.nlm.nih.gov/pubmed/36740704 http://dx.doi.org/10.1186/s12967-023-03932-y

Ejemplares similares

Integrated nontargeted and targeted metabolomics analyses amino acids metabolism in infantile hemangioma
por: Yang, Kaiying, et al.
Publicado: (2023)

Maternal and Perinatal Risk Factors for Infantile Hemangioma: A Matched Case-Control Study with a Large Sample Size
por: Gong, Xue, et al.
Publicado: (2022)

Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma
por: Li, Hui-Min, et al.
Publicado: (2017)

Analysis of Therapeutic Decisions for Infantile Hemangiomas: A Prospective Study Comparing the Hemangioma Severity Scale with the Infantile Hemangioma Referral Score
por: Qiu, Tong, et al.
Publicado: (2022)

Case Report: Bilateral symmetrical primary kaposiform hemangioendothelioma of the femur
por: Qiu, Tong, et al.
Publicado: (2022)

Infantile hepatic hemangiomas: looking backwards and forwards
por: Gong, Xue, et al.
Publicado: (2022)

Clinical Features of Segmental Infantile Hemangioma: A Prospective Study
por: Qiu, Tong, et al.
Publicado: (2021)

Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma
por: Yang, Kaiying, et al.
Publicado: (2021)

Oral antibiotic prophylaxis for infection in patients with vascular anomalies receiving sirolimus treatment: a multicenter retrospective study
por: Qiu, Tong, et al.
Publicado: (2023)

Role of PFKFB3-driven glycolysis in sepsis
por: Xiao, Min, et al.
Publicado: (2023)

Safety Evaluation of Oral Sirolimus in the Treatment of Childhood Diseases: A Systematic Review
por: Zhang, Zixin, et al.
Publicado: (2022)

Suppression of myeloid PFKFB3‐driven glycolysis protects mice from choroidal neovascularization
por: Liu, Zhiping, et al.
Publicado: (2022)

miR-1297 Suppresses Osteosarcoma Proliferation and Aerobic Glycolysis by Regulating PFKFB2
por: Pan, Xiaohui, et al.
Publicado: (2020)

Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response
por: Zeng, Hao, et al.
Publicado: (2022)

Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth
por: Hu, Jiahao, et al.
Publicado: (2022)

Mir‐488 alleviates chemoresistance and glycolysis of colorectal cancer by targeting PFKFB3
por: Deng, Xiaojing, et al.
Publicado: (2020)

Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
por: Yang, Qiuhua, et al.
Publicado: (2023)

Impact of age and tumor size on the development of the Kasabach–Merritt phenomenon in patients with kaposiform hemangioendothelioma: a retrospective cohort study
por: Zhou, Jiangyuan, et al.
Publicado: (2023)

Refractory kaposiform lymphangiomatosis relieved by splenectomy
por: Lan, Yuru, et al.
Publicado: (2023)

Quality of life in children with infantile hemangioma: a case control study
por: Wang, Chuan, et al.
Publicado: (2017)

Intolerable side effects during propranolol therapy for infantile hemangioma: frequency, risk factors and management
por: Ji, Yi, et al.
Publicado: (2018)

Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma
por: Li, Jun, et al.
Publicado: (2022)

Health-Related Quality of Life in Children With Kaposiform Hemangioendothelioma
por: Dai, Shiyi, et al.
Publicado: (2022)

PFKFB3-Mediated Glycolysis Boosts Fibroblast Activation and Subsequent Kidney Fibrosis
por: Yang, Qiuhua, et al.
Publicado: (2023)

PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb
por: Ryan, Terence E., et al.
Publicado: (2020)

Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis
por: Chen, Weimou, et al.
Publicado: (2021)

When to stop propranolol for infantile hemangioma
por: Chang, Lei, et al.
Publicado: (2017)

Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4
por: Shu, Yuxin, et al.
Publicado: (2016)

Management of Infantile Hemangiomas
por: Reddy, Kavitha K
Publicado: (2014)

Propranolol for Infantile Hemangiomas
por: Levy, Moise L.
Publicado: (2012)

Biology of Infantile Hemangioma
por: Itinteang, Tinte, et al.
Publicado: (2014)

Approach to Infantile Hemangiomas
por: Abraham, Anil, et al.
Publicado: (2016)

Infantile Periocular Hemangioma
por: Tavakoli, Mehdi, et al.
Publicado: (2017)

Update on infantile hemangioma
por: Jung, Hye Lim
Publicado: (2021)

Involvement of PFKFB3 in Pulmonary Arterial Hypertension Pathogenesis. Is It All about Glycolysis?
por: Bonnet, Sebastien, et al.
Publicado: (2019)

The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition
por: Emini Veseli, Besa, et al.
Publicado: (2021)

Infantile hemangioma models: is the needle in a haystack?
por: Kong, Meng, et al.
Publicado: (2023)

Signaling pathways in the development of infantile hemangioma
por: Ji, Yi, et al.
Publicado: (2014)

HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression
por: Wang, Yixin, et al.
Publicado: (2021)

Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
por: Lu, Chao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gsshlquqmp6a88d2mvlsvc2e5u