Cargando…

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying treatment exists. Neuroinflammation is central to the pathology progression, with evidence suggesting that microglia-released galectin-3 (gal3) plays a pivotal role by amplify...

Descripción completa

Detalles Bibliográficos
Autores principales: Arroyo-García, Luis Enrique, Bachiller, Sara, Ruiz, Rocío, Boza-Serrano, Antonio, Rodríguez-Moreno, Antonio, Deierborg, Tomas, Andrade-Talavera, Yuniesky, Fisahn, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901156/
https://www.ncbi.nlm.nih.gov/pubmed/36740709
http://dx.doi.org/10.1186/s40035-023-00338-0

Ejemplares similares