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Pathogenic tau decreases nuclear tension in cultured neurons

Neurodegenerative tauopathies, including Alzheimer’s disease, are pathologically defined by the presence of aggregated forms of tau protein in brains of affected individuals. Previous studies report that the negative effects of pathogenic tau on the actin cytoskeleton and microtubules cause a toxic...

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Detalles Bibliográficos
Autores principales: Sohn, Claira, Ma, Jiacheng, Ray, William J., Frost, Bess
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901542/
https://www.ncbi.nlm.nih.gov/pubmed/36756194
http://dx.doi.org/10.3389/fragi.2023.1058968