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GLX351322, a Novel NADPH Oxidase 4 Inhibitor, Attenuates TMJ Osteoarthritis by Inhibiting the ROS/MAPK/NF-κB Signaling Pathways
As a degenerative disease in joints, temporomandibular joint osteoarthritis (TMJOA) is characterized by progressive cartilage degradation, subchondral bone remodeling, and chronic synovitis, severely undermining functions and quality of life in patients. NADPH oxidase 4 (NOX4) contributes to reactiv...
Autores principales: | Zhen, Jinze, Chen, Xinwei, Mao, Yi, Xie, Xinru, Chen, Xuzhuo, Xu, Weifeng, Zhang, Shanyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902131/ https://www.ncbi.nlm.nih.gov/pubmed/36756301 http://dx.doi.org/10.1155/2023/1952348 |
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