Intrathecal dexmedetomidine attenuates mechanical allodynia through the downregulation of brain-derived neurotrophic factor in a mild traumatic brain injury rat model

BACKGROUND: This study evaluated the effects of dexmedetomidine and propofol on brain-derived neurotrophic factor level in the cerebrospinal fluid (c-BDNF) and mechanical allodynia in a mild traumatic brain injury (TBI) rat model. METHODS: After fixing the rat’s skull on a stereotactic frame under g...

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Detalles Bibliográficos
Autores principales: Jeon, Soeun, Baik, Jiseok, Kim, Jisu, Lee, Jiyoon, Do, Wangseok, Kim, Eunsoo, Lee, Hyeon Jeong, Kim, Haekyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Anesthesiologists 2023
Materias:
Experimental Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902181/
https://www.ncbi.nlm.nih.gov/pubmed/35760392
http://dx.doi.org/10.4097/kja.22209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902181/
https://www.ncbi.nlm.nih.gov/pubmed/35760392
http://dx.doi.org/10.4097/kja.22209

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