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Intrathecal dexmedetomidine attenuates mechanical allodynia through the downregulation of brain-derived neurotrophic factor in a mild traumatic brain injury rat model

BACKGROUND: This study evaluated the effects of dexmedetomidine and propofol on brain-derived neurotrophic factor level in the cerebrospinal fluid (c-BDNF) and mechanical allodynia in a mild traumatic brain injury (TBI) rat model. METHODS: After fixing the rat’s skull on a stereotactic frame under g...

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Detalles Bibliográficos
Autores principales:	Jeon, Soeun, Baik, Jiseok, Kim, Jisu, Lee, Jiyoon, Do, Wangseok, Kim, Eunsoo, Lee, Hyeon Jeong, Kim, Haekyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Anesthesiologists 2023
Materias:	Experimental Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902181/ https://www.ncbi.nlm.nih.gov/pubmed/35760392 http://dx.doi.org/10.4097/kja.22209

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