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The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions

The evolutionary conserved CCR4-NOT complex functions in the cytoplasm as the main mRNA deadenylase in both constitutive mRNA turnover and regulated mRNA decay pathways. The versatility of this complex is underpinned by its modular multi-subunit organization, with distinct structural modules actuati...

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Detalles Bibliográficos
Autores principales: Mauxion, Fabienne, Basquin, Jérôme, Ozgur, Sevim, Rame, Marion, Albrecht, Jana, Schäfer, Ingmar, Séraphin, Bertrand, Conti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902336/
https://www.ncbi.nlm.nih.gov/pubmed/36586408
http://dx.doi.org/10.1016/j.celrep.2022.111902