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Increased expression of the immunoproteasome subunits PSMB8 and PSMB9 by cancer cells correlate with better outcomes for triple-negative breast cancers

Proteasome dependency is a feature of many cancers that can be targeted by proteasome inhibitors. For some cancer types, notably breast cancer and triple-negative breast cancer (TNBC), high mRNA expression of a modified form of the proteasome, called the immunoproteasome (ImP), correlates with bette...

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Detalles Bibliográficos
Autores principales: Geoffroy, Karen, Araripe Saraiva, Bruna, Viens, Melissa, Béland, Delphine, Bourgeois-Daigneault, Marie-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902398/
https://www.ncbi.nlm.nih.gov/pubmed/36746983
http://dx.doi.org/10.1038/s41598-023-28940-2

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