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Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder

Adhesion G protein-coupled receptors (aGPCRs) are cell-surface proteins with large extracellular regions that bind to multiple ligands to regulate key biological functions including neurodevelopment and organogenesis. Modulating a single function of a specific aGPCR isoform while affecting no other...

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Detalles Bibliográficos
Autores principales:	Kordon, Szymon P., Dutka, Przemysław, Adamska, Justyna M., Bandekar, Sumit J., Leon, Katherine, Erramilli, Satchal K., Adams, Brock, Li, Jingxian, Kossiakoff, Anthony A., Araç, Demet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902482/ https://www.ncbi.nlm.nih.gov/pubmed/36746957 http://dx.doi.org/10.1038/s41467-023-36312-7

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