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Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017

BACKGROUND/AIMS: Uveal melanoma is the most common type of non-cutaneous melanoma and the most common ocular malignancy in the adult population, especially affecting Caucasians (98% of cases). Despite its low incidence rate, we have noted increasing incidence trends in recent years. METHODS: We anal...

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Autores principales: Conte, Santina, Lagacé, François, Ghazawi, Feras M., Cattelan, Leila, Nath, Siddharth, Dhillon, Jobanpreet, Nedjar, Hacene, Rahme, Elham, Sasseville, Denis, Burnier, Miguel N., Litvinov, Ivan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902509/
https://www.ncbi.nlm.nih.gov/pubmed/36760885
http://dx.doi.org/10.3389/fmed.2022.1001799
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author Conte, Santina
Lagacé, François
Ghazawi, Feras M.
Cattelan, Leila
Nath, Siddharth
Dhillon, Jobanpreet
Nedjar, Hacene
Rahme, Elham
Sasseville, Denis
Burnier, Miguel N.
Litvinov, Ivan V.
author_facet Conte, Santina
Lagacé, François
Ghazawi, Feras M.
Cattelan, Leila
Nath, Siddharth
Dhillon, Jobanpreet
Nedjar, Hacene
Rahme, Elham
Sasseville, Denis
Burnier, Miguel N.
Litvinov, Ivan V.
author_sort Conte, Santina
collection PubMed
description BACKGROUND/AIMS: Uveal melanoma is the most common type of non-cutaneous melanoma and the most common ocular malignancy in the adult population, especially affecting Caucasians (98% of cases). Despite its low incidence rate, we have noted increasing incidence trends in recent years. METHODS: We analyzed uveal melanoma incidence data using the Canadian Cancer Registry (CCR) for 2011–2017 years. The data was examined using the International Classification of Diseases for Oncology, Third Edition, codes for all uveal melanoma subtypes. The data for 2011–2017 was then compared to previously published work by our research group for uveal melanoma incidence in Canada between 1992 and 2010 using the same methodology. RESULTS: Between 2011 and 2017, 1,215 patients were diagnosed with uveal melanoma, 49% of whom were females. The percentage distribution of uveal melanoma between the sexes was similar between 1992–2010 and 2011–2017, whereby of the 2,215 diagnoses of uveal melanoma in 1992–2010, 47.9% were females. The change in the incidence rate for this cancer has doubled between 1992–2010 and 2011–2017, from 0.074 to 0.15 cases per million individuals per year. Our study documents that the Canadian 2011–2017 age-standardized incidence rate (ASIR) for uveal melanoma against the World Health Organization (WHO) 2000–2025 world population standard was 5.09 cases per million individuals per year (95% confidence interval, 4.73–5.44), as compared with the 1992–2010 rate of 3.34 cases per million individuals per year (95% confidence interval, CI 3.20 to 3.47). CONCLUSION: This work demonstrates an ongoing, steady increase in uveal melanoma incidence in Canada in recent years.
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spelling pubmed-99025092023-02-08 Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017 Conte, Santina Lagacé, François Ghazawi, Feras M. Cattelan, Leila Nath, Siddharth Dhillon, Jobanpreet Nedjar, Hacene Rahme, Elham Sasseville, Denis Burnier, Miguel N. Litvinov, Ivan V. Front Med (Lausanne) Medicine BACKGROUND/AIMS: Uveal melanoma is the most common type of non-cutaneous melanoma and the most common ocular malignancy in the adult population, especially affecting Caucasians (98% of cases). Despite its low incidence rate, we have noted increasing incidence trends in recent years. METHODS: We analyzed uveal melanoma incidence data using the Canadian Cancer Registry (CCR) for 2011–2017 years. The data was examined using the International Classification of Diseases for Oncology, Third Edition, codes for all uveal melanoma subtypes. The data for 2011–2017 was then compared to previously published work by our research group for uveal melanoma incidence in Canada between 1992 and 2010 using the same methodology. RESULTS: Between 2011 and 2017, 1,215 patients were diagnosed with uveal melanoma, 49% of whom were females. The percentage distribution of uveal melanoma between the sexes was similar between 1992–2010 and 2011–2017, whereby of the 2,215 diagnoses of uveal melanoma in 1992–2010, 47.9% were females. The change in the incidence rate for this cancer has doubled between 1992–2010 and 2011–2017, from 0.074 to 0.15 cases per million individuals per year. Our study documents that the Canadian 2011–2017 age-standardized incidence rate (ASIR) for uveal melanoma against the World Health Organization (WHO) 2000–2025 world population standard was 5.09 cases per million individuals per year (95% confidence interval, 4.73–5.44), as compared with the 1992–2010 rate of 3.34 cases per million individuals per year (95% confidence interval, CI 3.20 to 3.47). CONCLUSION: This work demonstrates an ongoing, steady increase in uveal melanoma incidence in Canada in recent years. Frontiers Media S.A. 2023-01-24 /pmc/articles/PMC9902509/ /pubmed/36760885 http://dx.doi.org/10.3389/fmed.2022.1001799 Text en Copyright © 2023 Conte, Lagacé, Ghazawi, Cattelan, Nath, Dhillon, Nedjar, Rahme, Sasseville, Burnier and Litvinov. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Conte, Santina
Lagacé, François
Ghazawi, Feras M.
Cattelan, Leila
Nath, Siddharth
Dhillon, Jobanpreet
Nedjar, Hacene
Rahme, Elham
Sasseville, Denis
Burnier, Miguel N.
Litvinov, Ivan V.
Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title_full Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title_fullStr Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title_full_unstemmed Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title_short Uveal melanoma incidence trends in Canada: 1992–2010 vs. 2011–2017
title_sort uveal melanoma incidence trends in canada: 1992–2010 vs. 2011–2017
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902509/
https://www.ncbi.nlm.nih.gov/pubmed/36760885
http://dx.doi.org/10.3389/fmed.2022.1001799
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