Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

Dietary restriction (DR) is a universal anti-aging intervention, which reduces age-related nervous system pathologies and neurological decline. The degree to which the neuroprotective effect of DR operates by attenuating cell intrinsic degradative processes rather than influencing non-cell autonomou...

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Detalles Bibliográficos
Autores principales: Birkisdóttir, María Björk, Van’t Sant, Lisanne J., Brandt, Renata M. C., Barnhoorn, Sander, Hoeijmakers, Jan H. J., Vermeij, Wilbert P., Jaarsma, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902592/
https://www.ncbi.nlm.nih.gov/pubmed/36760711
http://dx.doi.org/10.3389/fnagi.2022.1095801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902592/
https://www.ncbi.nlm.nih.gov/pubmed/36760711
http://dx.doi.org/10.3389/fnagi.2022.1095801

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