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Combined chemical transformation and biological transformation of artemisinin: A facile approach to diverse artemisinin derivatives
Introduction: Artemisinin (1) is a milestone compound in malaria treatment, and it exhibits a broad scope of bioactivities. Herein, sequential chemo-reduction and biotransformation of artemisinin were undertaken to obtain a series of artemisinin derivatives. Methods: First, 10-deoxyartemisinin (2) a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902651/ https://www.ncbi.nlm.nih.gov/pubmed/36760520 http://dx.doi.org/10.3389/fchem.2022.1089290 |