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Combined chemical transformation and biological transformation of artemisinin: A facile approach to diverse artemisinin derivatives

Introduction: Artemisinin (1) is a milestone compound in malaria treatment, and it exhibits a broad scope of bioactivities. Herein, sequential chemo-reduction and biotransformation of artemisinin were undertaken to obtain a series of artemisinin derivatives. Methods: First, 10-deoxyartemisinin (2) a...

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Detalles Bibliográficos
Autores principales: Gao, Xinna, Bai, Yue, Sun, Peng, Gao, Huimin, Yang, Lan, Zhang, Dong, Zhao, Yifan, Ma, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902651/
https://www.ncbi.nlm.nih.gov/pubmed/36760520
http://dx.doi.org/10.3389/fchem.2022.1089290

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