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Therapeutic potential of blocking GAPDH nitrosylation with CGP3466b in experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is a neuroinflammatory disease of the central nervous system (CNS). Although classically considered a demyelinating disease, neuroaxonal injury occurs in both the acute and chronic phases and represents a pathologic substrate of disability not targeted by current therapies. N...

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Detalles Bibliográficos
Autores principales: Godfrey, Wesley H., Hwang, Soonmyung, Cho, Kaho, Shanmukha, Shruthi, Gharibani, Payam, Abramson, Efrat, Kornberg, Michael Davin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902867/
https://www.ncbi.nlm.nih.gov/pubmed/36761918
http://dx.doi.org/10.3389/fneur.2022.979659