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Evaluation of probe-based ultra-sensitive detection of miRNA using a single-molecule fluorescence imaging method: miR-126 used as the model

This study proposed a new detection method of miRNA based on single-molecule fluorescence imaging, a method that has been successfully developed to measure the light signal of individual molecules labeled with proper fluorophores. We designed probes 1 and 2 to be labeled with Cy5 dye and BHQ2 quench...

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Detalles Bibliográficos
Autores principales: Liu, Longkai, Wang, Xiaoning, Li, Yan, Liu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902880/
https://www.ncbi.nlm.nih.gov/pubmed/36761298
http://dx.doi.org/10.3389/fbioe.2023.1081488

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