Cargando…
Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients
Citrullinated neoepitopes have emerged as key triggers of autoantibodies anti-citrullinated protein antibodies (ACPA) synthesis in rheumatoid arthritis (RA) patients. Apart from their critical role in homeostasis and thrombosis, platelets have a significant contribution to inflammation as well. Alth...
Autores principales: | Xu, Minjie, Du, Rong, Xing, Wenping, Chen, Xueting, Wan, Jian, Wang, Shengqing, Xiong, Li, Nandakumar, Kutty Selva, Holmdahl, Rikard, Geng, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902922/ https://www.ncbi.nlm.nih.gov/pubmed/36761728 http://dx.doi.org/10.3389/fimmu.2023.1084283 |
Ejemplares similares
-
Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2006) -
Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity
por: Carlsen, Stefan, et al.
Publicado: (2006) -
Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism
por: Wigerblad, Gustaf, et al.
Publicado: (2016) -
Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population
por: Terao, Chikashi, et al.
Publicado: (2015) -
Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells
por: Nandakumar, Kutty Selva, et al.
Publicado: (2004)