Cargando…

The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass

BACKGROUND: The sivelestat is a neutrophil elastase inhibitor thought to have an effect against acute lung injury (ALI) in patients after scheduled cardiac surgery. However, the beneficial effect of sivelestat in patients undergoing emergent cardiovascular surgery remains unclear. We aim to evaluate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Tuo, Tuoerxun, Tayierjiang, Chen, Xi, Yang, Cheng-Jin, Jiang, Chen-Yu, Zhu, Yi-Fan, Li, Ze-Shi, Jiang, Xin-Yi, Zhang, Hai-Tao, Zhang, He, Wang, Ya-Peng, Chen, Wei, Lu, Li-Chong, Ge, Min, Cheng, Yong-Qing, Wang, Dong-Jin, Zhou, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902923/ https://www.ncbi.nlm.nih.gov/pubmed/36761773 http://dx.doi.org/10.3389/fimmu.2023.1082830

Ejemplares similares

Corrigendum: The neutrophil elastase inhibitor, Sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass
por: Pan, Tuo, et al.
Publicado: (2023)

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats
por: Li, Guofu, et al.
Publicado: (2016)

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors
por: Crocetti, Letizia, et al.
Publicado: (2020)

Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats
por: Sun, Yali, et al.
Publicado: (2022)

Neutrophil Elastase Inhibitor Sivelestat Attenuates Myocardial Injury after Cardioplegic Arrest in Rat Hearts
por: Fujii, Masahiro, et al.
Publicado: (2019)

Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome
por: Aikawa, Naoki, et al.
Publicado: (2014)

Preclinical efficacy investigation of human neutrophil elastase inhibitor sivelestat in animal model of psoriasis
por: Zhukov, A. S., et al.
Publicado: (2021)

Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis
por: Miyoshi, Seigo, et al.
Publicado: (2013)

DNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps
por: Wang, Chun-Lian, et al.
Publicado: (2023)

The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium
por: Amaral, Ana, et al.
Publicado: (2020)

Suppressive effects of the neutrophil elastase inhibitor sivelestat sodium hydrate on interleukin-1β production in lipopolysaccharide-stimulated porcine whole blood
por: Kurimoto, Yasuyoshi, et al.
Publicado: (2020)

The role of neutrophil elastase in aortic valve calcification
por: Liu, Yan, et al.
Publicado: (2022)

Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes
por: Feng, Li, et al.
Publicado: (2013)

Renoprotective activity of sivelestat in severe acute pancreatitis in rats
por: WANG, HOUHONG, et al.
Publicado: (2013)

Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy?
por: Ding, Qiongli, et al.
Publicado: (2022)

Evaluation of low-dose colchicine in patients with cardiopulmonary bypass: study protocol for a randomised controlled trial
por: Zhang, He, et al.
Publicado: (2022)

Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice
por: Yang, Mei, et al.
Publicado: (2023)

Neutrophil elastase in bronchiectasis
por: Gramegna, Andrea, et al.
Publicado: (2017)

Isoflurane pre-treatment before cardiopulmonary bypass alleviates neutrophil accumulation in dog lungs
por: Du, Gui-Zhi, et al.
Publicado: (2011)

Correlation of PMN elastase and PMN elastase-to-neutrophil ratio with disease activity in patients with myositis
por: Wu, Siyu, et al.
Publicado: (2019)

Sivelestat Alleviates Atherosclerosis by Improving Intestinal Barrier Function and Reducing Endotoxemia
por: Nie, Hezhongrong, et al.
Publicado: (2022)

PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
por: Hou, Hsin-Han, et al.
Publicado: (2014)

Neutrophil elastase and its therapeutic effect on leukemia cells
por: JIANG, KAI-LING, et al.
Publicado: (2015)

Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis
por: Wen, Guanmei, et al.
Publicado: (2018)

The Role of Neutrophils and Neutrophil Elastase in Pneumococcal Pneumonia
por: Domon, Hisanori, et al.
Publicado: (2021)

Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers
por: Ho, Ai-Sheng, et al.
Publicado: (2014)

Sirtinol Inhibits Neutrophil Elastase Activity and Attenuates Lipopolysaccharide-Mediated Acute Lung Injury in Mice
por: Tsai, Yung-Fong, et al.
Publicado: (2015)

Neutrophil elastase: From mechanisms to therapeutic potential
por: Zeng, Weilin, et al.
Publicado: (2023)

Myocardial protective effect of sivelestat sodium in rat models with sepsis-induced myocarditis
por: Zhang, Rujun, et al.
Publicado: (2022)

The Role of Neutrophils and Neutrophil Elastase in Pulmonary Arterial Hypertension
por: Taylor, Shalina, et al.
Publicado: (2018)

Neutrophil Elastase and Chronic Lung Disease
por: Voynow, Judith A., et al.
Publicado: (2021)

Neutrophil Elastase Defects in Congenital Neutropenia
por: Rydzynska, Zuzanna, et al.
Publicado: (2021)

Flavonoids as inhibitors of human neutrophil elastase
por: Jakimiuk, Katarzyna, et al.
Publicado: (2021)

Neutrophil elastase inhibitory effects of pentacyclic triterpenoids from Eriobotrya japonica (loquat leaves)
por: Zhang, Jie, et al.
Publicado: (2019)

Oral neutrophil quantitation in patients undergoing elective cardiopulmonary bypass
por: Wilcox, ME, et al.
Publicado: (2012)

Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils
Publicado: (1989)

Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses
por: Koga, Hikari, et al.
Publicado: (2013)

Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase
por: Leahy, Darren, et al.
Publicado: (2021)

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
por: Papayannopoulos, Venizelos, et al.
Publicado: (2010)

Plasma Neutrophil Elastase and Elafin Imbalance Is Associated with Acute Respiratory Distress Syndrome (ARDS) Development
por: Wang, Zhaoxi, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_16ih8lb0oa0rh0kvj37hc8kr0u