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Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902939/ https://www.ncbi.nlm.nih.gov/pubmed/36762109 http://dx.doi.org/10.3389/fphar.2023.1036051 |
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author | Baral, Bikash |
author_facet | Baral, Bikash |
author_sort | Baral, Bikash |
collection | PubMed |
description | The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and advanced bactericidal properties of bacteriophages (bacteriophage therapy) may be one of the viable infection control options. It is evident, however, that the safe and regulated application of phage treatment will need extensive knowledge of the characteristics and behaviour of certain phage–bacterium systems. This mini review offers an overview of the potential for phage therapy as well as the constraints and obstacles it faces in becoming a commonly accepted infection management strategy. |
format | Online Article Text |
id | pubmed-9902939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99029392023-02-08 Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens Baral, Bikash Front Pharmacol Pharmacology The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and advanced bactericidal properties of bacteriophages (bacteriophage therapy) may be one of the viable infection control options. It is evident, however, that the safe and regulated application of phage treatment will need extensive knowledge of the characteristics and behaviour of certain phage–bacterium systems. This mini review offers an overview of the potential for phage therapy as well as the constraints and obstacles it faces in becoming a commonly accepted infection management strategy. Frontiers Media S.A. 2023-01-24 /pmc/articles/PMC9902939/ /pubmed/36762109 http://dx.doi.org/10.3389/fphar.2023.1036051 Text en Copyright © 2023 Baral. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Baral, Bikash Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title | Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title_full | Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title_fullStr | Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title_full_unstemmed | Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title_short | Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens |
title_sort | phages against killer superbugs: an enticing strategy against antibiotics-resistant pathogens |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902939/ https://www.ncbi.nlm.nih.gov/pubmed/36762109 http://dx.doi.org/10.3389/fphar.2023.1036051 |
work_keys_str_mv | AT baralbikash phagesagainstkillersuperbugsanenticingstrategyagainstantibioticsresistantpathogens |