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Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens

The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and a...

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Autor principal: Baral, Bikash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902939/
https://www.ncbi.nlm.nih.gov/pubmed/36762109
http://dx.doi.org/10.3389/fphar.2023.1036051
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author Baral, Bikash
author_facet Baral, Bikash
author_sort Baral, Bikash
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description The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and advanced bactericidal properties of bacteriophages (bacteriophage therapy) may be one of the viable infection control options. It is evident, however, that the safe and regulated application of phage treatment will need extensive knowledge of the characteristics and behaviour of certain phage–bacterium systems. This mini review offers an overview of the potential for phage therapy as well as the constraints and obstacles it faces in becoming a commonly accepted infection management strategy.
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spelling pubmed-99029392023-02-08 Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens Baral, Bikash Front Pharmacol Pharmacology The emerging resistivity of antibiotic resistance superbugs desire the need to resolve the global problem of antibiotic resistance. Among several other methods currently being adopted, one possible solution may be the development of supplemental therapies for antibiotics. The use of the normal and advanced bactericidal properties of bacteriophages (bacteriophage therapy) may be one of the viable infection control options. It is evident, however, that the safe and regulated application of phage treatment will need extensive knowledge of the characteristics and behaviour of certain phage–bacterium systems. This mini review offers an overview of the potential for phage therapy as well as the constraints and obstacles it faces in becoming a commonly accepted infection management strategy. Frontiers Media S.A. 2023-01-24 /pmc/articles/PMC9902939/ /pubmed/36762109 http://dx.doi.org/10.3389/fphar.2023.1036051 Text en Copyright © 2023 Baral. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Baral, Bikash
Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title_full Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title_fullStr Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title_full_unstemmed Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title_short Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
title_sort phages against killer superbugs: an enticing strategy against antibiotics-resistant pathogens
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9902939/
https://www.ncbi.nlm.nih.gov/pubmed/36762109
http://dx.doi.org/10.3389/fphar.2023.1036051
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