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Increased cysteine metabolism in PINK1 models of Parkinson's disease

Parkinson's disease (PD), an age-dependent neurodegenerative disease, is characterised by the selective loss of dopaminergic neurons in the substantia nigra (SN). Mitochondrial dysfunction is a hallmark of PD, and mutations in PINK1, a gene necessary for mitochondrial fitness, cause PD. Drosoph...

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Detalles Bibliográficos
Autores principales:	Travaglio, Marco, Michopoulos, Filippos, Yu, Yizhou, Popovic, Rebeka, Foster, Edmund, Coen, Muireann, Martins, L. Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903142/ https://www.ncbi.nlm.nih.gov/pubmed/36695500 http://dx.doi.org/10.1242/dmm.049727

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