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Tim Protein Structures Reveal a Unique Face for Ligand Binding
Tim molecules regulate T cell responses; however, the molecular basis of their ligand recognition remains largely unknown. In this issue of Immunity, Santiago et al. (2007) and Cao et al. (2007) report the crystal structures of several Tims and provide insights into the structure-function relationsh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903193/ https://www.ncbi.nlm.nih.gov/pubmed/17376389 http://dx.doi.org/10.1016/j.immuni.2007.03.004 |
Sumario: | Tim molecules regulate T cell responses; however, the molecular basis of their ligand recognition remains largely unknown. In this issue of Immunity, Santiago et al. (2007) and Cao et al. (2007) report the crystal structures of several Tims and provide insights into the structure-function relationship of these molecules. |
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