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Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903198/ https://www.ncbi.nlm.nih.gov/pubmed/36591647 http://dx.doi.org/10.1111/jch.14604 |
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author | Bao, Qiligeer Li, Yun Ma, Shouyuan Qiu, Jiaojiao Sun, Jin Su, Yongkang Zhang, Anhang Cai, Shuang Cheng, Bokai Li, Man Zhang, Yan Wang, Shuxia Zhu, Ping |
author_facet | Bao, Qiligeer Li, Yun Ma, Shouyuan Qiu, Jiaojiao Sun, Jin Su, Yongkang Zhang, Anhang Cai, Shuang Cheng, Bokai Li, Man Zhang, Yan Wang, Shuxia Zhu, Ping |
author_sort | Bao, Qiligeer |
collection | PubMed |
description | Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the relationship between the HTHW phenotype and LVH in patients with hypertension remains unknown. The present study aimed to investigate whether the HTHW phenotype is associated with LVH, using echocardiography in a cross‐sectional study involving 4470 middle‐aged and older Chinese patients with hypertension. Logistic regression analysis revealed that patients with the HTHW phenotype were 1.52‐fold more likely to experience LVH than those with normal triglyceride levels and normal waist circumference. This association was independent of age, sex, and other potentially confounding factors. In the stratified analysis, a stronger correlation was found among women, people of at least 70 years of age, and people with hyperuricemia. These results suggest that distinguishing the HTHW phenotype in patients with hypertension could serve as a simple and effective screening strategy for identifying people with a higher risk of developing LVH. |
format | Online Article Text |
id | pubmed-9903198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99031982023-02-09 Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients Bao, Qiligeer Li, Yun Ma, Shouyuan Qiu, Jiaojiao Sun, Jin Su, Yongkang Zhang, Anhang Cai, Shuang Cheng, Bokai Li, Man Zhang, Yan Wang, Shuxia Zhu, Ping J Clin Hypertens (Greenwich) Triglycerides Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the relationship between the HTHW phenotype and LVH in patients with hypertension remains unknown. The present study aimed to investigate whether the HTHW phenotype is associated with LVH, using echocardiography in a cross‐sectional study involving 4470 middle‐aged and older Chinese patients with hypertension. Logistic regression analysis revealed that patients with the HTHW phenotype were 1.52‐fold more likely to experience LVH than those with normal triglyceride levels and normal waist circumference. This association was independent of age, sex, and other potentially confounding factors. In the stratified analysis, a stronger correlation was found among women, people of at least 70 years of age, and people with hyperuricemia. These results suggest that distinguishing the HTHW phenotype in patients with hypertension could serve as a simple and effective screening strategy for identifying people with a higher risk of developing LVH. John Wiley and Sons Inc. 2023-01-02 /pmc/articles/PMC9903198/ /pubmed/36591647 http://dx.doi.org/10.1111/jch.14604 Text en © 2022 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Triglycerides Bao, Qiligeer Li, Yun Ma, Shouyuan Qiu, Jiaojiao Sun, Jin Su, Yongkang Zhang, Anhang Cai, Shuang Cheng, Bokai Li, Man Zhang, Yan Wang, Shuxia Zhu, Ping Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title | Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title_full | Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title_fullStr | Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title_full_unstemmed | Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title_short | Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients |
title_sort | hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in chinese hypertension patients |
topic | Triglycerides |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903198/ https://www.ncbi.nlm.nih.gov/pubmed/36591647 http://dx.doi.org/10.1111/jch.14604 |
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