Cargando…

Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients

Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Qiligeer, Li, Yun, Ma, Shouyuan, Qiu, Jiaojiao, Sun, Jin, Su, Yongkang, Zhang, Anhang, Cai, Shuang, Cheng, Bokai, Li, Man, Zhang, Yan, Wang, Shuxia, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903198/
https://www.ncbi.nlm.nih.gov/pubmed/36591647
http://dx.doi.org/10.1111/jch.14604
_version_ 1784883426849980416
author Bao, Qiligeer
Li, Yun
Ma, Shouyuan
Qiu, Jiaojiao
Sun, Jin
Su, Yongkang
Zhang, Anhang
Cai, Shuang
Cheng, Bokai
Li, Man
Zhang, Yan
Wang, Shuxia
Zhu, Ping
author_facet Bao, Qiligeer
Li, Yun
Ma, Shouyuan
Qiu, Jiaojiao
Sun, Jin
Su, Yongkang
Zhang, Anhang
Cai, Shuang
Cheng, Bokai
Li, Man
Zhang, Yan
Wang, Shuxia
Zhu, Ping
author_sort Bao, Qiligeer
collection PubMed
description Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the relationship between the HTHW phenotype and LVH in patients with hypertension remains unknown. The present study aimed to investigate whether the HTHW phenotype is associated with LVH, using echocardiography in a cross‐sectional study involving 4470 middle‐aged and older Chinese patients with hypertension. Logistic regression analysis revealed that patients with the HTHW phenotype were 1.52‐fold more likely to experience LVH than those with normal triglyceride levels and normal waist circumference. This association was independent of age, sex, and other potentially confounding factors. In the stratified analysis, a stronger correlation was found among women, people of at least 70 years of age, and people with hyperuricemia. These results suggest that distinguishing the HTHW phenotype in patients with hypertension could serve as a simple and effective screening strategy for identifying people with a higher risk of developing LVH.
format Online
Article
Text
id pubmed-9903198
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-99031982023-02-09 Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients Bao, Qiligeer Li, Yun Ma, Shouyuan Qiu, Jiaojiao Sun, Jin Su, Yongkang Zhang, Anhang Cai, Shuang Cheng, Bokai Li, Man Zhang, Yan Wang, Shuxia Zhu, Ping J Clin Hypertens (Greenwich) Triglycerides Left ventricular hypertrophy (LVH), the most common target organ damage in patients with hypertension, is closely related to excessive visceral adipose tissue (VAT) accumulation in the body. The hypertriglyceridemic waist (HTHW) phenotype can act as a surrogate marker of excessive VAT. However, the relationship between the HTHW phenotype and LVH in patients with hypertension remains unknown. The present study aimed to investigate whether the HTHW phenotype is associated with LVH, using echocardiography in a cross‐sectional study involving 4470 middle‐aged and older Chinese patients with hypertension. Logistic regression analysis revealed that patients with the HTHW phenotype were 1.52‐fold more likely to experience LVH than those with normal triglyceride levels and normal waist circumference. This association was independent of age, sex, and other potentially confounding factors. In the stratified analysis, a stronger correlation was found among women, people of at least 70 years of age, and people with hyperuricemia. These results suggest that distinguishing the HTHW phenotype in patients with hypertension could serve as a simple and effective screening strategy for identifying people with a higher risk of developing LVH. John Wiley and Sons Inc. 2023-01-02 /pmc/articles/PMC9903198/ /pubmed/36591647 http://dx.doi.org/10.1111/jch.14604 Text en © 2022 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Triglycerides
Bao, Qiligeer
Li, Yun
Ma, Shouyuan
Qiu, Jiaojiao
Sun, Jin
Su, Yongkang
Zhang, Anhang
Cai, Shuang
Cheng, Bokai
Li, Man
Zhang, Yan
Wang, Shuxia
Zhu, Ping
Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title_full Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title_fullStr Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title_full_unstemmed Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title_short Hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in Chinese hypertension patients
title_sort hypertriglyceridemic waist phenotype is associated with left ventricular hypertrophy in chinese hypertension patients
topic Triglycerides
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903198/
https://www.ncbi.nlm.nih.gov/pubmed/36591647
http://dx.doi.org/10.1111/jch.14604
work_keys_str_mv AT baoqiligeer hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT liyun hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT mashouyuan hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT qiujiaojiao hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT sunjin hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT suyongkang hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT zhanganhang hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT caishuang hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT chengbokai hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT liman hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT zhangyan hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT wangshuxia hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients
AT zhuping hypertriglyceridemicwaistphenotypeisassociatedwithleftventricularhypertrophyinchinesehypertensionpatients