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Collective synthesis of aspulvinone and its analogues by vinylogous aldol condensation of substituted tetronic acids with aldehydes

A mild, modular and efficient synthetic method with broad substrate scope was developed for aspulvinones. Nine natural aspulvinones were synthesized, six of which were for the first time. The aldol condensation delivered Z-configuration products predominantly in MeCN. Meanwhile, alkoxy exchange occu...

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Detalles Bibliográficos
Autores principales: Yu, Xiaotan, Gu, Xiaoxia, Zhao, Yunpeng, Wang, Fengqing, Sun, Weiguang, Qi, Changxing, Gu, Lianghu, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903353/
https://www.ncbi.nlm.nih.gov/pubmed/36760298
http://dx.doi.org/10.1039/d2ra08133d