Selective decrease in alpha(1)-antitrypsin levels in diabetic retinopathy: Could the levels of it be playing a role in the pathophysiology of diabetic retinopathy?

BACKGROUND & OBJECTIVES: Type 2 diabetes mellitus (T2DM) is known to induce inflammation and activation of neutrophils causing the release of neutrophil elastase (NE), a pro-inflammatory proteinase. The activity of NE is regulated by endogenous inhibitors alpha(1)-antitrypsin (α(1)-AT) and alpha...

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Detalles Bibliográficos
Autores principales: Kunder, Mamatha, Lakshmaiah, V., Kutty, A.V. Moideen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903389/
https://www.ncbi.nlm.nih.gov/pubmed/36124492
http://dx.doi.org/10.4103/ijmr.IJMR_1293_19

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