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Myeloid cells protect corneal nerves against sterile injury through negative-feedback regulation of TLR2–IL-6 axis

BACKGROUND: Mounting evidence suggests that the immune system plays detrimental or protective roles in nerve injury and repair. MAIN BODY: Herein we report that both CD11b(hi)Ly6G(hi) and CD11b(hi)Ly6C(hi)Ly6G(lo) myeloid cells are required to protect corneal nerves against sterile corneal injury. S...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Ju, Kim, Hyeon Ji, Ko, Jung Hwa, Oh, Joo Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903461/
https://www.ncbi.nlm.nih.gov/pubmed/36750851
http://dx.doi.org/10.1186/s12974-023-02710-3