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Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis

BACKGROUND: The novel sodium-glucose co-transporter 2 inhibitor (SGLT2i) potentially ameliorates heart failure and reduces cardiac arrhythmia. Cardiac fibrosis plays a pivotal role in the pathophysiology of HF and atrial myopathy, but the effect of SGLT2i on fibrogenesis remains to be elucidated. Th...

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Detalles Bibliográficos
Autores principales:	Chung, Cheng-Chih, Lin, Yung-Kuo, Chen, Yao-Chang, Kao, Yu-Hsun, Yeh, Yung-Hsin, Trang, Nguyen Ngoc, Chen, Yi-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903522/ https://www.ncbi.nlm.nih.gov/pubmed/36747205 http://dx.doi.org/10.1186/s12933-023-01756-0

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