Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta, and beta loci

T cell receptors (TCRs) recognize peptide fragments presented by the major histocompatibility complex (MHC) and are critical to T cell-mediated immunity. Recent data have indicated that genetic diversity within TCR-encoding gene regions is underexplored, limiting understanding of the impact of TCR l...

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Detalles Bibliográficos
Autores principales: Rodriguez, Oscar L., Silver, Catherine A., Shields, Kaitlyn, Smith, Melissa L., Watson, Corey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903726/
https://www.ncbi.nlm.nih.gov/pubmed/36778049
http://dx.doi.org/10.1016/j.xgen.2022.100228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903726/
https://www.ncbi.nlm.nih.gov/pubmed/36778049
http://dx.doi.org/10.1016/j.xgen.2022.100228

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