Unscrambling cancer genomes via integrated analysis of structural variation and copy number

Complex somatic genomic rearrangements and copy number alterations are hallmarks of nearly all cancers. We have developed an algorithm, LINX, to aid interpretation of structural variant and copy number data derived from short-read, whole-genome sequencing. LINX classifies raw structural variant call...

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Detalles Bibliográficos
Autores principales: Shale, Charles, Cameron, Daniel L., Baber, Jonathan, Wong, Marie, Cowley, Mark J., Papenfuss, Anthony T., Cuppen, Edwin, Priestley, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903802/
https://www.ncbi.nlm.nih.gov/pubmed/36776527
http://dx.doi.org/10.1016/j.xgen.2022.100112

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