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The eternal quest for self-improvement of somatic cells
Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903819/ https://www.ncbi.nlm.nih.gov/pubmed/36778659 http://dx.doi.org/10.1016/j.xgen.2022.100094 |
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author | Campbell, Peter J. |
author_facet | Campbell, Peter J. |
author_sort | Campbell, Peter J. |
collection | PubMed |
description | Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro. |
format | Online Article Text |
id | pubmed-9903819 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-99038192023-02-10 The eternal quest for self-improvement of somatic cells Campbell, Peter J. Cell Genom Preview Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro. Elsevier 2022-02-09 /pmc/articles/PMC9903819/ /pubmed/36778659 http://dx.doi.org/10.1016/j.xgen.2022.100094 Text en © 2022 The Author https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Preview Campbell, Peter J. The eternal quest for self-improvement of somatic cells |
title | The eternal quest for self-improvement of somatic cells |
title_full | The eternal quest for self-improvement of somatic cells |
title_fullStr | The eternal quest for self-improvement of somatic cells |
title_full_unstemmed | The eternal quest for self-improvement of somatic cells |
title_short | The eternal quest for self-improvement of somatic cells |
title_sort | eternal quest for self-improvement of somatic cells |
topic | Preview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903819/ https://www.ncbi.nlm.nih.gov/pubmed/36778659 http://dx.doi.org/10.1016/j.xgen.2022.100094 |
work_keys_str_mv | AT campbellpeterj theeternalquestforselfimprovementofsomaticcells AT campbellpeterj eternalquestforselfimprovementofsomaticcells |