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Circulating DNA fragmentomics and cancer screening
The high fragmentation of nuclear circulating DNA (cirDNA) relies on chromatin organization and protection or packaging within mononucleosomes, the smallest and the most stabilized structure in the bloodstream. The detection of differing size patterns, termed fragmentomics, exploits information abou...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903826/ https://www.ncbi.nlm.nih.gov/pubmed/36777187 http://dx.doi.org/10.1016/j.xgen.2022.100242 |