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Circulating DNA fragmentomics and cancer screening

The high fragmentation of nuclear circulating DNA (cirDNA) relies on chromatin organization and protection or packaging within mononucleosomes, the smallest and the most stabilized structure in the bloodstream. The detection of differing size patterns, termed fragmentomics, exploits information abou...

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Detalles Bibliográficos
Autor principal: Thierry, A.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9903826/
https://www.ncbi.nlm.nih.gov/pubmed/36777187
http://dx.doi.org/10.1016/j.xgen.2022.100242