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Inflammasome-independent NLRP3 function enforces ATM activity in response to genotoxic stress
NLRP3 is a pattern recognition receptor with a well-documented role in inducing inflammasome assembly in response to cellular stress. Deregulation of its activity leads to many inflammatory disorders including gouty arthritis, Alzheimer disease, and cancer. Whereas its role in the context of cancer...
Autores principales: | Bodnar-Wachtel, Mélanie, Huber, Anne-Laure, Gorry, Julie, Hacot, Sabine, Burlet, Delphine, Gérossier, Laetitia, Guey, Baptiste, Goutagny, Nadège, Bartosch, Birke, Ballot, Elise, Lecuelle, Julie, Truntzer, Caroline, Ghiringhelli, François, Py, Bénédicte F, Couté, Yohann, Ballesta, Annabelle, Lantuejoul, Sylvie, Hall, Janet, Tissier, Agnès, Petrilli, Virginie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904227/ https://www.ncbi.nlm.nih.gov/pubmed/36746533 http://dx.doi.org/10.26508/lsa.202201494 |
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