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A dynamic causal modeling of the second outbreak of COVID-19 in Italy

While the vaccination campaign against COVID-19 is having its positive impact, we retrospectively analyze the causal impact of some decisions made by the Italian government on the second outbreak of the SARS-CoV-2 pandemic in Italy, when no vaccine was available. First, we analyze the causal impact...

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Autores principales: Bilancia, Massimo, Vitale, Domenico, Manca, Fabio, Perchinunno, Paola, Santacroce, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904269/
https://www.ncbi.nlm.nih.gov/pubmed/36776481
http://dx.doi.org/10.1007/s10182-023-00469-9
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author Bilancia, Massimo
Vitale, Domenico
Manca, Fabio
Perchinunno, Paola
Santacroce, Luigi
author_facet Bilancia, Massimo
Vitale, Domenico
Manca, Fabio
Perchinunno, Paola
Santacroce, Luigi
author_sort Bilancia, Massimo
collection PubMed
description While the vaccination campaign against COVID-19 is having its positive impact, we retrospectively analyze the causal impact of some decisions made by the Italian government on the second outbreak of the SARS-CoV-2 pandemic in Italy, when no vaccine was available. First, we analyze the causal impact of reopenings after the first lockdown in 2020. In addition, we also analyze the impact of reopening schools in September 2020. Our results provide an unprecedented opportunity to evaluate the causal relationship between the relaxation of restrictions and the transmission in the community of a highly contagious respiratory virus that causes severe illness in the absence of prophylactic vaccination programs. We present a purely data-analytic approach based on a Bayesian methodology and discuss possible interpretations of the results obtained and implications for policy makers.
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spelling pubmed-99042692023-02-07 A dynamic causal modeling of the second outbreak of COVID-19 in Italy Bilancia, Massimo Vitale, Domenico Manca, Fabio Perchinunno, Paola Santacroce, Luigi Adv Stat Anal Original Paper While the vaccination campaign against COVID-19 is having its positive impact, we retrospectively analyze the causal impact of some decisions made by the Italian government on the second outbreak of the SARS-CoV-2 pandemic in Italy, when no vaccine was available. First, we analyze the causal impact of reopenings after the first lockdown in 2020. In addition, we also analyze the impact of reopening schools in September 2020. Our results provide an unprecedented opportunity to evaluate the causal relationship between the relaxation of restrictions and the transmission in the community of a highly contagious respiratory virus that causes severe illness in the absence of prophylactic vaccination programs. We present a purely data-analytic approach based on a Bayesian methodology and discuss possible interpretations of the results obtained and implications for policy makers. Springer Berlin Heidelberg 2023-02-07 /pmc/articles/PMC9904269/ /pubmed/36776481 http://dx.doi.org/10.1007/s10182-023-00469-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Bilancia, Massimo
Vitale, Domenico
Manca, Fabio
Perchinunno, Paola
Santacroce, Luigi
A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title_full A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title_fullStr A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title_full_unstemmed A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title_short A dynamic causal modeling of the second outbreak of COVID-19 in Italy
title_sort dynamic causal modeling of the second outbreak of covid-19 in italy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904269/
https://www.ncbi.nlm.nih.gov/pubmed/36776481
http://dx.doi.org/10.1007/s10182-023-00469-9
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