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Novel Pt(IV) prodrug self-assembled nanoparticles with enhanced blood circulation stability and improved antitumor capacity of oxaliplatin for cancer therapy

Pt(IV) compounds are regarded as prodrugs of active Pt(II) drugs (i.e. cisplatin, carboplatin, and oxaliplatin) and burgeoned as the most ideal candidates to substitute Pt(II) anticancer drugs with severe side effects. Nanoparticle drug delivery systems have been widely introduced to deliver Pt(IV)...

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Detalles Bibliográficos
Autores principales: Fu, Yuanlei, Kong, Ying, Li, Xiangping, Cheng, Dongfang, Hou, Yuqian, Li, Yan, Li, Tongfang, Xiao, Yani, Zhang, Qiuyan, Rong, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904295/
https://www.ncbi.nlm.nih.gov/pubmed/36744299
http://dx.doi.org/10.1080/10717544.2023.2171158