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Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats

OBJECTIVES: To observe the protective effects of dexmedetomidine (Dex) postconditioning on myocardial ischemia/reperfusion injury (IRI) and to explore its potential molecular mechanisms. METHODS: One-hundred forty-seven male Sprague-Dawley rats were randomly divided into five groups receiving the di...

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Detalles Bibliográficos
Autores principales: Hu, Bin, Tian, Tian, Li, Xin-Tao, Hao, Pei-Pei, Liu, Wei-Chao, Chen, Ying-Gui, Jiang, Tian-Yu, Chen, Pei-Shan, Cheng, Yi, Xue, Fu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904316/
https://www.ncbi.nlm.nih.gov/pubmed/36738240
http://dx.doi.org/10.1080/13510002.2022.2158526