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The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease

Magnetic sphincter augmentation (MSA) has been designed as a less disruptive and more standardized laparoscopic surgical procedure than fundoplication for patients with early stage gastroesophageal reflux disease (GERD). We analyzed the more recent literature in search of updates regarding indicatio...

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Autores principales: Bonavina, Luigi, Boyle, Nick, Schoppmann, Sebastian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904435/
https://www.ncbi.nlm.nih.gov/pubmed/33883422
http://dx.doi.org/10.1097/MOG.0000000000000748
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author Bonavina, Luigi
Boyle, Nick
Schoppmann, Sebastian F.
author_facet Bonavina, Luigi
Boyle, Nick
Schoppmann, Sebastian F.
author_sort Bonavina, Luigi
collection PubMed
description Magnetic sphincter augmentation (MSA) has been designed as a less disruptive and more standardized laparoscopic surgical procedure than fundoplication for patients with early stage gastroesophageal reflux disease (GERD). We analyzed the more recent literature in search of updates regarding indications, technique, perioperative management, and long-term outcomes. RECENT FINDINGS: Over the years, the procedure of MSA has evolved to including full hiatus repair rather than relying on the preservation of the phreno-esophageal ligament. Restoring the mechanical synergy between the lower esophageal sphincter and the crural diaphragm has the potential to further enhance the antireflux barrier. The adoption of this approach has led to expand the indications from early stage disease to different scenarios including patients with high esophageal acid exposure, atypical symptoms, large hiatal hernias, Barrett's esophagus, postbariatric surgery, and previously failed fundoplication. SUMMARY: MSA has a favorable side-effect profile and is highly effective in reducing typical reflux symptoms, medication dependency, and esophageal acid exposure. Excellent outcomes have been confirmed over a 12-year follow-up, indicating that the operation has the potential to prevent GERD progression. Further studies are needed to confirm the cost-effectiveness of this procedure in patients with more advanced disease-stage and prior gastric surgery. A randomized control trial comparing MSA with fundoplication could raise the level of evidence and the strength of recommendation.
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spelling pubmed-99044352023-02-14 The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease Bonavina, Luigi Boyle, Nick Schoppmann, Sebastian F. Curr Opin Gastroenterol ESOPHAGUS: Edited by Stuart J. Spechler Magnetic sphincter augmentation (MSA) has been designed as a less disruptive and more standardized laparoscopic surgical procedure than fundoplication for patients with early stage gastroesophageal reflux disease (GERD). We analyzed the more recent literature in search of updates regarding indications, technique, perioperative management, and long-term outcomes. RECENT FINDINGS: Over the years, the procedure of MSA has evolved to including full hiatus repair rather than relying on the preservation of the phreno-esophageal ligament. Restoring the mechanical synergy between the lower esophageal sphincter and the crural diaphragm has the potential to further enhance the antireflux barrier. The adoption of this approach has led to expand the indications from early stage disease to different scenarios including patients with high esophageal acid exposure, atypical symptoms, large hiatal hernias, Barrett's esophagus, postbariatric surgery, and previously failed fundoplication. SUMMARY: MSA has a favorable side-effect profile and is highly effective in reducing typical reflux symptoms, medication dependency, and esophageal acid exposure. Excellent outcomes have been confirmed over a 12-year follow-up, indicating that the operation has the potential to prevent GERD progression. Further studies are needed to confirm the cost-effectiveness of this procedure in patients with more advanced disease-stage and prior gastric surgery. A randomized control trial comparing MSA with fundoplication could raise the level of evidence and the strength of recommendation. Lippincott Williams & Wilkins 2021-07 2021-04-20 /pmc/articles/PMC9904435/ /pubmed/33883422 http://dx.doi.org/10.1097/MOG.0000000000000748 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle ESOPHAGUS: Edited by Stuart J. Spechler
Bonavina, Luigi
Boyle, Nick
Schoppmann, Sebastian F.
The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title_full The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title_fullStr The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title_full_unstemmed The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title_short The role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
title_sort role of magnetic sphincter augmentation in the treatment of gastroesophageal reflux disease
topic ESOPHAGUS: Edited by Stuart J. Spechler
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9904435/
https://www.ncbi.nlm.nih.gov/pubmed/33883422
http://dx.doi.org/10.1097/MOG.0000000000000748
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